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A study reported in the British Journal of Psychiatry observed that administering progesterone from the middle trimester of pregnancy for relief of the symptoms of toxemia had some unexpected benefits: "A significant improvement in educational performance was demonstrated among children [whose mothers] received progesterone before the sixteenth week" following conception; and after giving birth their mothers seemed to have greater success at breastfeeding. Clinical observations involving ninety children whose mothers received progesterone were summarized thus: